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Article

Characterisation of insomnia as an environmental risk factor for asthma via Mendelian randomization and gene environment interaction.

Scientific reports - 8 Nov 2021

Kim Dong Jun, Ha Tae-Woong, Jung Hae Un, Baek Eun Ju, Lee Won Jun, Kim Han Kyul, Kang Ji-One, Won Sungho, Lim Ji Eun, Oh Bermseok

Abstract excerpt

Asthma is a complex disease that is reportedly associated with insomnia. However, the causal directionality of this association is still unclear. We used asthma and insomnia-associated single nucleotide polymorphisms (SNPs) and genome-wide association study (GWAS) summary statistics to test the causal directionality between insomnia and asthma via Mendelian randomization (MR) analysis. We also performed a...

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Identifiers

PMID: 34750467
DOI: 10.1038/s41598-021-01291-6
PMCID: PMC8576024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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