Article
New insights into causal relationship between serum lipids, obesity, and asthma: a Mendelian randomization study.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Sept 2025
Sun Jialiang, Chen Lanlan, Zhao Peiliang, Bai Xinquan, Nie Shu, Li Yanan
Abstract excerpt
OBJECTIVE: To identify causal risk factors for asthma using a Mendelian randomization (MR) approach. METHODS: Genetic variants associated with the exposures at the genome-wide significance level (p < 5 × 10 - 8) were obtained from corresponding genome-wide association studies. Summary-level statistical data for asthma were obtained from the UK Biobank (UKB) and the FinnGen Consortia. Univariate and multivariate...
Read the complete abstract on PubMedTopics
- Humans
- Asthma
- Mendelian Randomization Analysis
- Obesity
- Body Mass Index
- Genome-Wide Association Study
