Article
Maternal HLA-C2 and 14 bp insertion in HLA-G is associated with recurrent implantation failure after in vitro fertilization treatment.
Tissue antigens - 1 Dec 2014
Lashley L E E L O, van der Westerlaken L A J, Haasnoot G W, Drabbels J J M, Spruyt-Gerritse M J, Scherjon S A, Claas F H J
Abstract excerpt
The major rate-limiting step in in vitro fertilization (IVF) success appears to be the implantation of the semi-allogeneic embryo into the maternal endometrium. To determine possible risk factors of recurrent failure of embryos to implant, we investigated immunogenetic determinants as level of human leukocyte antigen (HLA) histocompatibility, frequency of killer-cell immunoglobulin-like receptors (KIR) and HLA-C...
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