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Article

LncRNA DLEU1 is overexpressed in premature ovarian failure and sponges miR-146b-5p to increase granulosa cell apoptosis

5 Nov 2021

Abstract excerpt

BACKGROUND: miR-146b-5p has been reported to participate in premature ovarian failure (POF) in mice. However, its role in POF patients is unclear. We predicted that miR-146b-5p might interact with lncRNA DLEU1, a crucial player in ovarian cancer. We then explored the interaction between DLEU1 and miR-146b-5p. METHODS: Expression of DLEU1 and miR-146b-5p in POF and control ovary tissues was determined by RT-qPCR....

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PMID: 34740384
DOI: 10.1186/s13048-021-00905-x

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