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lncRNA-FMR6 directly binds SAV1 to increase apoptosis of granulosa cells in premature ovarian failure

1 Apr 2023

Abstract excerpt

BACKGROUND: A regulatory mechanism of lncRNA binding to protein has been detected in premature ovarian failure (POF). Therefore, this study was expected to illustrate the mechanism of lncRNA-FMR6 and SAV1 regulating POF. METHODS: Follicular fluid and ovarian granulosa cells (OGCs) from POF patients and healthy volunteers were collected. Using RT-qPCR and western blotting, lncRNA-FMR6 and SAV1 expression were...

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PMID: 37005611
DOI: 10.1186/s13048-023-01121-5

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