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Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency

17 Oct 2023

Abstract excerpt

BACKGROUND: Premature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ovary. Granulosa cells (GCs) around oocytes are critical for folliculogenesis, and GC dysfunction is one of the important etiologies of POI. The aim of this study was to explore the potential biomarkers of POI by identifying hub genes and analyze the correlation of biomarkers with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37848988
DOI: 10.1186/s13048-023-01266-3

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