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Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models

25 Oct 2021

Abstract excerpt

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy. Vaccination and infection have led to widespread humoral immunity against the pandemic founder (Wu-Hu-1). Against this background, it is critical to assess the outcomes of subsequent immunization with variant antigens. It is not yet clear...

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PMID: 34723224
DOI: 10.1016/j.xcrm.2021.100450

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