Article
Histopathological investigation of the 1p/19q-codeleted gliomas resected following alkylating agent chemotherapy.
Journal of neuro-oncology - 1 Dec 2021
Kanazawa Tokunori, Ohara Kentaro, Kitamura Yohei, Nakaya Masato, Yoshida Kazunari, Sasaki Hikaru
Abstract excerpt
PURPOSE: Lower grade gliomas with 1p/19q codeletion are often responsive to chemotherapy, and several of these have been treated using upfront chemotherapy and subsequent resection following tumor volume decrease. This study aimed to elucidate the histological changes and the mechanism of recurrence after alkylating agent chemotherapy in 1p/19-codeleted gliomas. METHODS: Fourteen 1p/19q-codeleted gliomas resected...
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