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Article

Impact of 1p/19q codeletion and histology on outcomes of anaplastic gliomas treated with radiation therapy and temozolomide.

International journal of radiation oncology, biology, physics - 1 Feb 2015

Speirs Christina K, Simpson Joseph R, Robinson Clifford G, DeWees Todd A, Tran David D, Linette Gerry, Chicoine Michael R, Dacey Ralph G, Rich Keith M, Dowling Joshua L, Leuthardt Eric C, Zipfel Gregory J, Kim Albert H, Huang Jiayi

Abstract excerpt

PURPOSE: Anaplastic gliomas represent a heterogeneous group of primary high-grade brain tumors, and the optimal postoperative treatment remains controversial. In this report, we present our institutional data on the clinical outcomes of radiation therapy (RT) plus temozolomide (RT + TMZ) for anaplastic gliomas, stratified by histology and 1p/19q codeletion. METHODS AND MATERIALS: A single-institution...

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PMID: 25636755
DOI: 10.1016/j.ijrobp.2014.10.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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