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Article

Fecal Microbiota Transplantation Modulates Renal Phenotype in the Humanized Mouse Model of IgA Nephropathy.

Frontiers in immunology - 1 Jan 2021

Lauriero Gabriella, Abbad Lilia, Vacca Mirco, Celano Giuseppe, Chemouny Jonathan M, Calasso Maria, Berthelot Laureline, Gesualdo Loreto, De Angelis Maria, Monteiro Renato C

Abstract excerpt

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis. Several observations suggest that gut microbiota could be implicated in IgAN pathophysiology. Aiming at exploring whether microbiota modulation is able to influence disease outcome, we performed fecal microbiota transplantation (FMT) from healthy controls (HC-sbjs), non-progressor (NP-pts) and progressor (P-pts) IgAN patients to...

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Identifiers

PMID: 34712223
DOI: 10.3389/fimmu.2021.694787
PMCID: PMC8546224

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