Creation of a non-Western humanized gnotobiotic mouse model through the transplantation of rural African fecal microbiota

Abstract excerpt

ABSTRACT Gut microbiota are increasingly being recognized as a contributing factor in the etiology of numerous diseases and as a potential determinant in the immune response to various treatments. Recent work has suggested that the suboptimal immunogenic response to vaccination in low- and middle-income countries may be associated with differences in the gut microbiome, which are known to be substantially...

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