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Article

The gut-kidney axis in IgA nephropathy: role of microbiota and diet on genetic predisposition.

Pediatric nephrology (Berlin, Germany) - 1 Jan 2018

Coppo Rosanna

Abstract excerpt

Recent data suggest that gut-associated lymphoid tissue (GALT) plays a major role in the development of immunoglobulin A (IgA) nephropathy (IgAN). A genome-wide association study showed that most loci associated with the risk of IgAN are also associated with immune-mediated inflammatory bowel diseases, maintenance of the intestinal barrier and regulation of response to gut pathogens. Studies involving...

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Source

Identifiers

PMID: 28389744
DOI: 10.1007/s00467-017-3652-1

Genes

GALT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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