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Article

Toll-like receptor 9 affects severity of IgA nephropathy.

Journal of the American Society of Nephrology : JASN - 1 Dec 2008

Suzuki Hitoshi, Suzuki Yusuke, Narita Ichiei, Aizawa Masashi, Kihara Masao, Yamanaka Takahiro, Kanou Tatsuya, Tsukaguchi Hiroyasu, Novak Jan, Horikoshi Satoshi, Tomino Yasuhiko

Abstract excerpt

Environmental pathogens are suspected to aggravate renal injury in IgA nephropathy (IgAN), but neither underlying mechanisms nor specific exogenous antigens have been identified. In this study, a genome-wide scan of ddY mice, which spontaneously develop IgAN, was performed, and myeloid differentiation factor 88 (MyD88) was identified as a candidate gene for progression of renal injury (chi(2) = 21.103, P =...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18776126
DOI: 10.1681/ASN.2007121311
PMCID: PMC2588104

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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