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Article

Clinical use of Molecular Data in Thyroid Nodules and Cancer

18 May 2023

Abstract excerpt

Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main drivers in differentiated TC pathogenesis are single-point mutations and gene fusions in components of the Mitogen-activated protein kinase (MAPK) and phosphoinositide-3-kinase-protein kinase B/Akt (PI3K/Akt) pathways. Other important...

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PMID: 37200449
DOI: 10.1210/clinem/dgad282

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