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Article

Negative regulation by proBDNF signaling of peripheral neurogenesis in the sensory ganglia of adult rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Dec 2021

Ma Wei, Yang Jin-Wei, Wang Xian-Bin, Luo Tao, Zhou Lei, Lagares Alfonso, Li Hongyun, Liang Zhang, Liu Kuang-Pin, Zang Cheng-Hao, Li Chun-Yan, Wu Zhen, Guo Jian-Hui, Zhou Xin-Fu, Li Li-Yan

Abstract excerpt

Neurogenesis in the adult brain is well recognized and plays a critical role in the maintenance of brain function and homeostasis. However, whether neurogenesis also occurs in the adult peripheral nervous system remains unknown. Here, using sensory ganglia (dorsal root ganglia, DRGs) as a model, we show that neurogenesis also occurs in the peripheral nervous system, but in a manner different from that in the...

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Identifiers

PMID: 34700232
DOI: 10.1016/j.biopha.2021.112273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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