Article
Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 19 Nov 2008
McGraw Hillary F, Nechiporuk Alexei, Raible David W
Abstract excerpt
The proneural transcription factor neurogenin 1 (neurog1) has been shown to be a key regulator of dorsal root ganglion (DRG) neuron development. Here we use a novel transgenic zebrafish line to demonstrate that the neural crest population that gives rise to DRG neurons becomes fate restricted to a neuronal/glial precursor before the onset of neurog1 function. We generated a stable transgenic zebrafish line that...
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