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Article

Delayed but not loss of gliogenesis in Rbpj-deficient trigeminal ganglion.

International journal of clinical and experimental pathology - 1 Jan 2013

Hu Ze-Lan, Zhang Xin, Shi Ming, Tian Zhi-Wen, Huang Ying, Chen Jia-Yin, Ding Yu-Qiang

Abstract excerpt

Somatosensory ganglia including dorsal root ganglion (DRG) and trigeminal ganglion (TG) are derived from a common pool of neural crest stem cells (NCCs), and are good systems to study the mechanisms of neurogenesis and gliogenesis. Previous studies have reported that deletion of Rbpj, a critical integrator of activation signals from all Notch receptors, in NCCs and their derived cells resulted in the delayed...

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PMID: 23826407
PMCID: PMC3693191

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