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Article

Fusion of the Paired Box 3 (PAX3) and Myocardin (MYOCD) Genes in Pediatric Rhabdomyosarcoma

1 Jan 2021

Abstract excerpt

BACKGROUND/AIM: Fusions of the paired box 3 gene (PAX3 in 2q36) with different partners have been reported in rhabdomyosarcomas and biphenotypic sinonasal sarcomas. We herein report the myocardin (MYOCD on 17p12) gene as a novel PAX3-fusion partner in a pediatric tumor with adverse clinical outcome. MATERIALS AND METHODS: A rhabdomyo-sarcoma found in a 10-year-old girl was studied using a range of genetic...

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Identifiers

PMID: 34697065
DOI: 10.21873/cgp.20293

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