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Article

Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.

Oncogene - 10 Sept 2001

Barr F G

Abstract excerpt

The chromosomal translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are characteristic of alveolar rhabdomyosarcoma, a pediatric soft tissue cancer related to the striated muscle lineage. These translocations rearrange PAX3 and PAX7, members of the paired box transcription factor family, and juxtapose these genes with FKHR, a member of the fork head transcription factor family. This juxtaposition generates...

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Topics

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Share to Forkhead Box Protein O1
Share to Forkhead Transcription Factors
Share to Oncogene Proteins, Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Paired Box Transcription Factors

Share to PAX3 Transcription Factor

Share to PAX7 Transcription Factor

Share to Transcriptional Activation

Share to Translocation, Genetic

Source

Identifiers

PMID: 11607823
DOI: 10.1038/sj.onc.1204599

Genes

PAX3
PAX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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