CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.

doi:10.1016/j.jmoldx.2023.06.008

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CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.

The Journal of molecular diagnostics : JMD - 1 Sept 2023

Pratt Victoria M, Cavallari Larisa H, Fulmer Makenzie L, Gaedigk Andrea, Hachad Houda, Ji Yuan, Kalman Lisa V, Ly Reynold C, Moyer Ann M, Scott Stuart A, van Schaik Ron H N, Whirl-Carrillo Michelle, Weck Karen E

Abstract excerpt

The goals of the Association for Molecular Pathology Clinical Practice Committee's Pharmacogenomics (PGx) Working Group are to define the key attributes of pharmacogenetic alleles recommended for clinical testing and a minimum set of variants that should be included in clinical PGx genotyping assays. This document series provides recommendations for a minimum panel of variant alleles (tier 1) and an extended...

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PMID: 37419245
DOI: 10.1016/j.jmoldx.2023.06.008
PMCID: PMC10565868

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