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Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation Strategies

1 Jan 2023

Abstract excerpt

In cell transplantation therapy, mesenchymal stem cells(MSCs)are ideal seed cells due to their easy acquisition and cultivation, strong regenerative capacity, multi-directional differentiation abilities, and immunomodulatory effects. Autologous MSCs are better applicable compared with allogeneic MSCs in clinical practice. The elderly are the main population for cell transplantation therapy, but as donor aging,...

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PMID: 37196126
DOI: 10.14336/ad.2023.0208

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