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Article

Insulin-like Growth Factor 1 Signaling in Mammalian Hearing.

Genes - 29 Sept 2021

García-Mato Ángela, Cervantes Blanca, Murillo-Cuesta Silvia, Rodríguez-de la Rosa Lourdes, Varela-Nieto Isabel

Abstract excerpt

Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family. Factors, receptors and IGF-binding proteins form the IGF system, which has multiple roles in mammalian development,...

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Topics

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Share to Growth Hormone and Insulin-like Growth Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing, Cochlea, Tinnitus, Genetics

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Share to Insulin-Like Growth Factor I

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Source

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Identifiers

PMID: 34680948
DOI: 10.3390/genes12101553
PMCID: PMC8535591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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