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Article

Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays.

Hearing research - 1 Dec 2015

Rodríguez-de la Rosa Lourdes, Sánchez-Calderón Hortensia, Contreras Julio, Murillo-Cuesta Silvia, Falagan Sandra, Avendaño Carlos, Dopazo Joaquín, Varela-Nieto Isabel, Milo Marta

Abstract excerpt

The auditory and vestibular organs form the inner ear and have a common developmental origin. Insulin like growth factor 1 (IGF-1) has a central role in the development of the cochlea and maintenance of hearing. Its deficiency causes sensorineural hearing loss in man and mice. During chicken early development, IGF-1 modulates neurogenesis of the cochleovestibular ganglion but no further studies have been...

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PMID: 26341476
DOI: 10.1016/j.heares.2015.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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