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SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation.

Cell research - 1 Dec 2021

Xu Gang, Li Ying, Zhang Shengyuan, Peng Haoran, Wang Yunyun, Li Dekang, Jin Taijie, He Zhuohao, Tong Yilun, Qi Chunting, Wu Guowei, Dong Kangyun, Gou Jizhou, Liu Yang, Xiao Tongyang, Qu Jing, Li Liang, Liu Liang, Zhao Ping, Zhang Zheng, Yuan Junying

Abstract excerpt

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the ongoing global pandemic that poses substantial challenges to public health worldwide. A subset of COVID-19 patients experience systemic inflammatory response, known as cytokine storm, which may lead to death. Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an important mediator of...

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Identifiers

PMID: 34663909
DOI: 10.1038/s41422-021-00578-7
PMCID: PMC8522117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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