Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed Therapies

21 Feb 2022

Abstract excerpt

Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a significant global health emergency with new variants in some cases evading current therapies and approved vaccines. COVID-19 presents with a broad spectrum of acute and long-term manifestations. Severe COVID-19 is characterized by dysregulated cytokine release profile, dysfunctional immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to Inflammasome and immune disorders
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35265086
DOI: 10.3389/fimmu.2022.842740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed TherapiesPMID 35265086Read ↗

Caspases in COVID-19 Disease and Sequela and the Therapeutic Potential of Caspase InhibitorsSemantic proximity Read ↗

Programmed cell death: the pathways to severe COVID-19?Semantic proximity Read ↗

Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19Semantic proximity Read ↗

The roles of cellular protease interactions in viral infections and programmed cell death: a lesson learned from the SARS-CoV-2 outbreak and COVID-19 pandemicSemantic proximity Read ↗

Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosisSemantic proximity Read ↗

Inflammasome activation and pulmonary viral loads define two distinct clinical outcomes in COVID-19Semantic proximity Read ↗

Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targetsSemantic proximity Read ↗

Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosisSemantic proximity Read ↗

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patientsSemantic proximity Read ↗

Targeting of the NLRP3 Inflammasome for early COVID-19Semantic proximity Read ↗

Inflammasome Genetic Variants Are Associated with Protection to Clinical Severity of COVID-19 among Patients from Rio de Janeiro, Brazil.Semantic proximity Read ↗

Caspases in Cell Death, Inflammation, and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.