Article
Allergies, genetic polymorphisms of Th2 interleukins, and childhood acute lymphoblastic leukemia: The ESTELLE study.
Pediatric blood & cancer - 1 Mar 2022
Ajrouche Roula, Chandab Ghinaj, Petit Arnaud, Strullu Marion, Nelken Brigitte, Plat Geneviève, Michel Gérard, Domenech Carine, Clavel Jacqueline, Bonaventure Audrey
Abstract excerpt
CONTEXT: A negative association between a history of allergy and childhood acute lymphoblastic leukemia (ALL) has been reported in previous studies, but remains debated. This work aimed to investigate this association accounting for genetic polymorphisms of the Th2 pathway cytokines (IL4, IL10, IL13, and IL4R). METHODS: Analyses were based on the French case-control study ESTELLE (2010-2011). The complete sample...
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