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Article

Association between nitric oxide synthase T-786C genetic polymorphism and chronic kidney disease: Meta-analysis incorporating trial sequential analysis.

PloS one - 1 Jan 2021

Hsiao Po-Jen, Chiu Chih-Chien, Tsai Dung-Jang, Ko Pi-Shao, Chen Ying-Kai, Cheng Hao, Su Wen, Lu Kuo-Cheng, Su Sui-Lung

Abstract excerpt

BACKGROUND: Several meta-analyses of the relationship between endothelial nitric oxide synthase (eNOS) T-786C gene polymorphism and chronic kidney disease (CKD) have been published. However, the results of these studies were inconsistent, and it is undetermined whether sample sizes are sufficient to reach a definite conclusion. OBJECTIVE: To elucidate the relationship between T-786C and CKD by combining previous...

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Identifiers

PMID: 34662360
DOI: 10.1371/journal.pone.0258789
PMCID: PMC8523046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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