Article
PhoPQ regulates acidic glycerophospholipid content of the Salmonella Typhimurium outer membrane.
Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 2014
Dalebroux Zachary D, Matamouros Susana, Whittington Dale, Bishop Russell E, Miller Samuel I
Abstract excerpt
Gram-negative bacteria have two lipid membranes separated by a periplasmic space containing peptidoglycan. The surface bilayer, or outer membrane (OM), provides a barrier to toxic molecules, including host cationic antimicrobial peptides (CAMPs). The OM comprises an outer leaflet of lipid A, the bioactive component of lipopolysaccharide (LPS), and an inner leaflet of glycerophospholipids (GPLs). The structure of...
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