Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in Macrophages

27 Mar 2019

Abstract excerpt

Staphylococcus aureus is a major cause of infectious disease. Liver Kupffer cells (KCs) are responsible for sequestering and destroying S. aureus through the phagolysosomal pathway. Proteins belonging to the COMMD family emerge as key intracellular regulators of protein trafficking, but the role of COMMD10 in macrophage-mediated S. aureus eradication is unknown. Here we report that COMMD10 in macrophages was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine and Purinergic Signaling
Share to Calcium signaling and nucleotide metabolism
Share to Cystic Fibrosis Research Advances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30959277
DOI: 10.1016/j.isci.2019.03.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in MacrophagesPMID 30959277Read ↗

Intracellular Staphylococcus aureus and host cell death pathwaysSemantic proximity Read ↗

Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages.Semantic proximity Read ↗

The Role of Macrophages in Staphylococcus aureus InfectionSemantic proximity Read ↗

Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular SurvivalSemantic proximity Read ↗

Neonatal granulocytic MDSCs possess phagocytic properties during bacterial infectionSemantic proximity Read ↗

<i>Staphylococcus aureus</i> derived extracellular vesicles trigger multiple inflammatory pathways in host cells and deliver their RNA cargo following their internalization and lysis within late endosomesSemantic proximity Read ↗

Pyroptosis in neutrophils: Multimodal integration of inflammasome and regulated cell death signaling pathwaysSemantic proximity Read ↗

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.Semantic proximity Read ↗

Functional and Proteomic Dissection of the Contributions of CodY, SigB and the Hibernation Promoting Factor HPF to Interactions of Staphylococcus aureus USA300 with Human Lung Epithelial CellsSemantic proximity Read ↗

Staphylococcus aureus reprograms CASP8 (caspase 8) signaling to evade cell death and XenophagySemantic proximity Read ↗

Autophagy in Staphylococcus aureus InfectionSemantic proximity Read ↗

Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.