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Article

Mesenchymal Stem Cell-derived Exosomes Affect Macrophage Phenotype: A Cell-free Strategy for the Treatment of Skeletal Muscle Disorders.

Current molecular medicine - 1 Jan 2023

Su Gang, Lei Xiaoting, Wang Zhenyu, Xie Weiqiang, Wen Donghong, Wu Yucheng

Abstract excerpt

The process of tissue damage, repair, and regeneration in the skeletal muscle system involves complex inflammatory processes. Factors released in the inflammatory microenvironment can affect the phenotypic changes of macrophages, thereby changing the inflammatory process, making macrophages an important target for tissue repair treatment. Mesenchymal stem cells exert anti-inflammatory effects by regulating immune...

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PMID: 35546766
DOI: 10.2174/1566524022666220511123625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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