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Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus

9 Sept 2021

Abstract excerpt

Methicillin-resistant S. aureus (MRSA) are resistant to beta-lactams, but synergistic activity between beta-lactams and glycopeptides/lipopeptides is common. Many have attributed this synergy to the beta-lactam-glycopeptide seesaw effect; however, this association has not been rigorously tested. The objective of this study was to determine whether the seesaw effect is necessary for synergy and to measure the...

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PMID: 34646861
DOI: 10.3389/fmolb.2021.688357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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