Article
Potent synergy of ceftobiprole plus daptomycin against multiple strains of Staphylococcus aureus with various resistance phenotypes.
The Journal of antimicrobial chemotherapy - 1 Nov 2014
Barber Katie E, Werth Brian J, Ireland Cortney E, Stone Nicole E, Nonejuie Poochit, Sakoulas George, Pogliano Joseph, Rybak Michael J
Abstract excerpt
OBJECTIVES: Ceftobiprole is a broad-spectrum cephalosporin that demonstrates activity against Staphylococcus aureus resistant to methicillin, including strains with reduced susceptibility to glycopeptides and lipopeptides. The addition of this agent provides a potential therapeutic option for difficult-to-treat infections. Synergy has been demonstrated between β-lactams combined with glycopeptides and...
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