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Article

ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis.

Arthritis research & therapy - 25 May 2012

Wang Chin-Man, Ho Huei-Huang, Chang Su-Wei, Wu Yeong-Jian Jan, Lin Jing-Chi, Chang Pi-Yueh, Wu Jianming, Chen Ji-Yih

Abstract excerpt

INTRODUCTION: Ankylosing spondylitis (AS) is a familial, heritable disease specified by syndesmophyte formation leading to an ankylosed spine. Endoplasmic reticulum aminopeptidase 1 (ERAP1) genetic variations have been widely proved to be associated with AS in several ethnic populations. The aim of this study was to investigate whether ERAP1 single nucleotide polymorphisms (SNPs) are associated with AS...

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Source

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Identifiers

PMID: 22632381
DOI: 10.1186/ar3855
PMCID: PMC3446506

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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