Article
[Pathogenesis of ankylosing spondylitis-mechanisms of disease manifestation and chronicity].
Zeitschrift fur Rheumatologie - 1 Jun 2004
Märker-Hermann E, Frauendorf E, Zeidler H, Sieper J
Abstract excerpt
Despite intensive research during the last three decades, it is still not clear which precise mechanisms determine the interactions between host factors (HLA-B27 and other genes, cytokines, T lymphocytes) and microbial factors leading to the manifestation and chronicity of ankylosing spondylitis (AS). Rheumatologists and histopathologists have focused their interest on decoding the immune-mediated inflammatory...
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