Article
Methylene tetrahydrofolate reductase (MTHFR) and vascular endothelial growth factor (VEGF) polymorphisms in Brazilian patients with Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC).
Clinics (Sao Paulo, Brazil) - 1 Jan 2021
Carvalho Sylene C R, Vasconcelos Luydson R S, Fonseca Leonardo da, Carmo Rodrigo F, Tomitão Michele T, Aroucha Dayse C B L, Pereira Leila M M B, Stefano José Tadeu, Ribeiro-Júnior Ulysses, Oliveira Claudia P, Carrilho Flair J
Abstract excerpt
OBJECTIVE: The folate pathway is involved in hepatic carcinogenesis and angiogenesis. Polymorphisms in genes related to such processes, including methylene tetrahydrofolate reductase (MTHFR) and vascular endothelial growth factor (VEGF)] may play an important role in the development of hepatocellular carcinoma (HCC). The objective of this study was to evaluate MTHFR and VEGF polymorphisms in Brazilian patients...
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