Article
Single nucleotide polymorphism in DNMT3B promoter and its association with hepatocellular carcinoma in a Moroccan population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2009
Ezzikouri Sayeh, El Feydi Abdellah Essaid, Benazzouz Mustapha, Afifi Rajae, El Kihal Latifa, Hassar Mohammed, Akil Abdellah, Pineau Pascal, Benjelloun Soumaya
Abstract excerpt
Hepatocellular carcinoma is a major malignant tumor characterized in all areas by the disparity of risk between genders. The molecular bases of such disparity are still poorly understood. DNA-methyltransferase-3B (DNMT3B) may play an oncogenic role during tumorigenesis, and its genetic variants have been consistently associated with risk of several cancers, but a single study has investigated their roles in...
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