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Article

Causal associations of intelligence with schizophrenia and bipolar disorder: A Mendelian randomization analysis

1 Jan 2021

Abstract excerpt

BACKGROUND: Intelligence is inversely associated with schizophrenia (SCZ) and bipolar disorder (BD); it remains unclear whether low intelligence is a cause or consequence. We investigated causal associations of intelligence with SCZ or BD risk and a shared risk between SCZ and BD and SCZ-specific risk. METHODS: To estimate putative causal associations, we performed multi-single nucleotide polymorphism (SNP)...

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PMID: 34641990
DOI: 10.1192/j.eurpsy.2021.2237

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