Article
Breed-specific reference sequence optimized mapping accuracy of NGS analyses for pigs.
BMC genomics - 12 Oct 2021
Wang Dan, Yang Liu, Ning Chao, Liu Jian-Feng, Zhao Xingbo
Abstract excerpt
BACKGROUND: Reference sequences play a vital role in next-generation sequencing (NGS), impacting mapping quality during genome analyses. However, reference genomes usually do not represent the full range of genetic diversity of a species as a result of geographical divergence and independent demographic events of different populations. For the mitochondrial genome (mitogenome), which occurs in high copy numbers...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.