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Article

Identification of Rare LRP5 Variants in a Cohort of Males with Impaired Bone Mass.

International journal of molecular sciences - 7 Oct 2021

Rocca Maria Santa, Minervini Giovanni, Di Nisio Andrea, Merico Maurizio, Bueno Marinas Maria, De Toni Luca, Pilichou Kalliopi, Garolla Andrea, Foresta Carlo, Ferlin Alberto

Abstract excerpt

Osteoporosis is the most common bone disease characterized by reduced bone mass and increased bone fragility. Genetic contribution is one of the main causes of primary osteoporosis; therefore, both genders are affected by this skeletal disorder. Nonetheless, osteoporosis in men has received little attention, thus being underestimated and undertreated. The aim of this study was to identify novel genetic variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34639175
DOI: 10.3390/ijms221910834
PMCID: PMC8509722

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