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B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy

28 Sept 2021

Abstract excerpt

Defects in the apoptosis mechanism stimulate cancer cell growth and survival. B cell lymphoma 2 (Bcl-2) is an anti-apoptotic molecule that plays a central role in apoptosis. Bcl-2 is the founding constituent of the Bcl-2 protein family of apoptosis controllers, the primary apoptosis regulators linked with cancer. Bcl-2 has been identified as being over-expressed in several cancers. Bcl-2 is induced by protein...

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PMID: 34638779
DOI: 10.3390/ijms221910442

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