Article
CRISPR-Cas Technology as a Revolutionary Genome Editing tool: Mechanisms and Biomedical Applications.
Iranian biomedical journal - 1 Sept 2023
Ebrahimi S, Khosravi Mohammad Ali, Raz Abbasali, Karimipoor Morteza, Parvizi Parviz
Abstract excerpt
Programmable nucleases are powerful genomic tools for precise genome editing. These tools precisely recognize, remove, or change DNA at a defined site, thereby, stimulating cellular DNA repair pathways that can cause mutations or accurate replacement or deletion/insertion of a sequence. CRISPR-Cas9 system is the most potent and useful genome editing technique adapted from the defense immune system of certain...
Topics
- Animals
- Humans
- Gene Editing
- CRISPR-Cas Systems
- Bacteria
- Mutation
- DNA