Article
Clinical significance of the immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells of adult T-cell leukaemia-lymphoma patients receiving mogamulizumab.
British journal of haematology - 1 Feb 2022
Nosaka Kisato, Kusumoto Shigeru, Nakano Nobuaki, Choi Ilseung, Yoshimitsu Makoto, Imaizumi Yoshitaka, Hidaka Michihiro, Sasaki Hidenori, Makiyama Junya, Ohtsuka Eiichi, Jo Tatsuro, Ogata Masao, Ito Asahi, Yonekura Kentaro, Tatetsu Hiro, Kato Takeharu, Kawakita Toshiro, Suehiro Youko, Ishitsuka Kenji, Iida Shinsuke, Matsutani Takaji, Utsunomiya Atae, Ueda Ryuzo, Ishida Takashi
Abstract excerpt
'Monitoring of immune responses following mogamulizumab-containing treatment in patients with adult T-cell leukaemia-lymphoma (ATL)' (MIMOGA) is a multicentre prospective clinical study (UMIN000008696). In the MIMOGA study, we found that a lower percentage of CD2- CD19+ B cells in peripheral blood mononuclear cells (PBMC) was a significant unfavourable prognostic factor for overall survival (OS). Accordingly, we...
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