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Article

Phenotypic and Genetic Heterogeneity in a Thai Glucokinase MODY Family Reveals the Complexity of Young-Onset Diabetes.

Frontiers in endocrinology - 1 Jan 2021

Thewjitcharoen Yotsapon, Wanothayaroj Ekgaluck, Krittiyawong Sirinate, Nakasatien Soontaree, Tsoi Tsz Fung, Lim Cadmon K P, Chan Juliana C N, Himathongkam Thep

Abstract excerpt

Glucokinase-Maturity-Onset Diabetes of the Young (GCK-MODY) is characterized by asymptomatic, non-progressive and fasting hyperglycemia, albeit not without phenotypic variability. We used next generation sequencing (NGS) to screen for 34 MODY genes in a non-obese person with familial young-onset diabetes followed by screening in 24 family members within three generations with varying presentations of young-onset...

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Identifiers

PMID: 34630320
DOI: 10.3389/fendo.2021.690343
PMCID: PMC8498575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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