Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of maturity-onset diabetes of the young through targeted next-generation sequencing in Thai patients with atypical diabetes in real-world practice.

Frontiers in endocrinology - 1 Jan 2026

Thewjitcharoen Yotsapon, Chatchomchuan Waralee, Wanothayaroj Ekgaluck, Nakasatien Soontaree, Lim Cadmon K P, Himathongkam Thep, Chan Juliana C N

Abstract excerpt

Introduction: Maturity-onset diabetes of the young (MODY) is often misdiagnosed as either autoimmune type 1 diabetes (T1D) or polygenic type 2 diabetes (T2D), resulting in missed diagnosis and inappropriate treatment. Differentiating MODY from T2D is challenging in Asians with low body mass index (BMI) and strong family history. The clinical impact of genetic testing in a real-world case series of Thai patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germinal Center Kinases

Share to Hepatocyte Nuclear Factor 1-alpha

Share to High-Throughput Nucleotide Sequencing

Share to Southeast Asian People

Share to Thailand

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41694565
DOI: 10.3389/fendo.2026.1717121
PMCID: PMC12893939

Genes

GCK
HNF1A
HNF1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of maturity-onset diabetes of the young through targeted next-generation sequencing in Thai patients with atypical diabetes in real-world practice.PMID 41694565Read ↗

Phenotypic and Genetic Heterogeneity in a Thai Glucokinase MODY Family Reveals the Complexity of Young-Onset Diabetes.Semantic proximity Read ↗

Focusing on Rare Variants Related to Maturity-Onset Diabetes of the Young in Children.Semantic proximity Read ↗

Maturity-onset diabetes of the young in a large Portuguese cohort.Semantic proximity Read ↗

Next-generation sequencing identifies monogenic diabetes in 16% of patients with late adolescence/adult-onset diabetes selected on a clinical basis: a cross-sectional analysisSemantic proximity Read ↗

MODY is prevalent in later-onset diabetes, has potential for targeted therapy but is challenging to identifySemantic proximity Read ↗

The Rare and Atypical Diabetes Network (RADIANT) Study: Design and Early ResultsSemantic proximity Read ↗

How do I diagnose Maturity Onset Diabetes of the Young in my patients?Semantic proximity Read ↗

Genetic and Clinical Characteristics of Monogenic Diabetes in Japan: A Nationwide Study by the Japan Diabetes Society.Semantic proximity Read ↗

Precision Diagnosis of Maturity-Onset Diabetes of the Young with Next-Generation Sequencing: Findings from the MODY-IST Study in Adult Patients.Semantic proximity Read ↗

Genetic spectrum and treatment implications of maturity-onset diabetes of the young in the eastern Black Sea region of Türkiye: a combined adult and pediatric cohort of 296 patients with identification of rare and novel variants.Semantic proximity Read ↗

Low genetic confirmation rate in South Indian subjects with a clinical diagnosis of maturity-onset diabetes of the young (MODY) who underwent targeted next-generation sequencing for 13 genes.Semantic proximity Read ↗

Identification of monogenic diabetes in an Australian cohort using the Exeter maturity-onset diabetes of the young (MODY) probability calculator and next-generation sequencing gene panel testing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.