Article
Phylogenomic analysis and Mycobacterium tuberculosis antibiotic resistance prediction by whole-genome sequencing from clinical isolates of Caldas, Colombia.
PloS one - 1 Jan 2021
Sánchez-Corrales Lusayda, Tovar-Aguirre Olga Lucía, Galeano-Vanegas Narmer Fernando, Castaño Jiménez Paula Alejandra, Martínez-Vega Ruth Arali, Maldonado-Londoño Carlos Ernesto, Hernández-Botero Johan Sebastián, Siller-López Fernando
Abstract excerpt
Mycobacterium tuberculosis (M. tuberculosis) was the pathogen responsible for the highest number of deaths from infectious diseases in the world, before the arrival of the COVID-19 pandemic. Whole genome sequencing (WGS) has contributed to the understanding of genetic diversity, the mechanisms involved in drug resistance and the transmission dynamics of this pathogen. The object of this study is to use WGS for...
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