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Comprehensive Drug Resistance Characterization of Pulmonary Tuberculosis in Algeria: Insights on Mycobacterium tuberculosis Strains by Whole-Genome Sequencing.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jul 2023

Benremila Dalila, Djoudi Ferhat, Gharout-Sait Alima, Kheloufi Slimane, Spitaleri Andrea, Battaglia Simone, Cabibbe Andrea Maurizio, Cirillo Daniela Maria

Abstract excerpt

In this study, we aimed to characterize drug-resistant strains by whole-genome sequencing (WGS), to describe the spreading lineages and the history of transmission. Drug susceptibility testing was performed by 96-well broth microdilution plates. The genomic DNA was extracted and purified; libraries were prepared and run on the Illumina NextSeq500 System. Among 82 isolates, 21 tuberculosis (TB) isolates (25.6%)...

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Identifiers

PMID: 37115530
DOI: 10.1089/mdr.2022.0321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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