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Article

Gene polymorphisms of insulin secretion signaling pathway associated with clopidogrel resistance in Han Chinese population.

Journal of clinical laboratory analysis - 1 Nov 2021

Zhong Jinyan, Yu Qinglin, Zheng Nan, Su Jia, Zheng Xiaowei, Zheng Liangrong, Chen Xiaomin

Abstract excerpt

BACKGROUND: Due to the loss of responsiveness to insulin, diabetes mellitus (DM) patients develop increased platelet reactivity and reduced response to antiplatelet agents. Nevertheless, the relationship between the single-nucleotide polymorphisms (SNP) of the signal pathway gene of insulin secretion and the effect of clopidogrel is elusive. METHODS: Blood samples were collected from patients administered with...

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PMID: 34609028
DOI: 10.1002/jcla.23970
PMCID: PMC8605143

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