Article
Pathophysiologic Mechanisms of Insulin Secretion and Signaling-Related Genes in Etiology of Polycystic Ovary Syndrome.
Genetics research - 1 Jan 2021
Shaaban Zahra, Khoradmehr Arezoo, Amiri-Yekta Amir, Nowzari Fariborz, Jafarzadeh Shirazi Mohammad Reza, Tamadon Amin
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women. PCOS is characterized by anovulation, hyperandrogenism, polycystic ovaries, insulin resistance, and obesity. Despite the finding that the genetic origin of PCOS is well demonstrated in previous twin and familial clustering studies, genes and factors that can exactly explain the PCOS pathophysiology are not known. Objective(s). In this review,...
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