Article
Effect of Donor NKG2D Polymorphism on Relapse after Haploidentical Transplantation with Post-Transplantation Cyclophosphamide.
Transplantation and cellular therapy - 1 Jan 2022
Ido Kentaro, Koh Hideo, Hirose Asao, Seto Toshiyuki, Makuuchi Yosuke, Kuno Masatomo, Takakuwa Teruhito, Okamura Hiroshi, Nanno Satoru, Nakamae Mika, Nishimoto Mitsutaka, Nakashima Yasuhiro, Hino Masayuki, Nakamae Hirohisa
Abstract excerpt
NKG2D-mediated cytotoxicity is regulated by the single nucleotide polymorphism rs1049174, and its antitumor effect has been observed in various clinical settings. There are no previously published data on the influence of donor rs1049174 polymorphism on HLA-haploidentical allogeneic hematopoietic cell transplantation using post-transplantation cyclophosphamide (PTCy-haplo). We aimed to investigate the effect of...
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