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Transcriptomics paving the way for improved diagnostics and precision medicine of acute leukemia

1 Oct 2021

Abstract excerpt

Transcriptional profiling of acute leukemia, specifically by RNA-sequencing or whole transcriptome sequencing (WTS), has provided fundamental insights into its underlying disease biology and allows unbiased detection of oncogenic gene fusions, as well as of gene expression signatures that can be used for improved disease classification. While used as a research tool for many years, RNA-sequencing is becoming...

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PMID: 34606984
DOI: 10.1016/j.semcancer.2021.09.013

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